Anatomy A215 Virtual Microscopy
Lymph Nodes
 
 

Lymph nodes have a capsule and trabeculae. Lymphatic vessels enter the node at various points, penetrating the capsule. Inside the lymph node are two general regions, an outer cortex and an inner medulla. Identify these and their components on this slide of a single large LYMPH NODE. The little box in the picture to the left is seen enlarged below.
  • The cortex has numerous trabeculae and densely packed lymphocytes, often as lymphatic nodules
    (also called lymphoid follicles).
  • The medulla is composed of larger interconnected sinuses (spaces) and a meshwork of trabeculae giving this region a lighter staining appearance.

In these images, you can see the lymphatic follicles in the cortex, some demonstrating germinal center formation.

 

 
 
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